The impact of vitamin D status on changes in bone mineral density during treatment with bisphosphonates and after discontinuation following long-term use in post-menopausal osteoporosis.

A similar trend in the percentage and absolute changes in BMD at the hip was observed when comparing BMD changes between the women according their serum 25 (OH) vitamin D concentrations using the optimum cut-off level of 70 nmol/L (9) (Figure 2 ), (Patients with serum 25 (OH)D < 70 nmol/L: -0.004 [0.007], serum 25 (OH)D >70 nmol/L: 0.01 [0.004] g/cm 2 , p = 0.06) although the results failed to reach statistical significance.

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