Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts.

Arthritis Res Ther · 2006 · PMC1794522 · PMID 17129375

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did not reach statistical significanceno p-value reported

Moerover, although the phosphorylation of PKB was slightly upregulated in OA (19.2 ± 1.0 relative units, n = 3) compared to normal (14.1 ± 1.5 relative units, n = 3) after a 5 minute IGF-1 stimulation, this difference did not reach statistical significance.

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