Synergy or independence? Deciphering the interaction of HLA Class I and NK cell KIR alleles in early HIV-1 disease progression.

PLoS Pathog · 2007 · PMC1853116 · PMID 17447840

Europe PMC DOI

hedged sentences

0.2700

closest p · 5.4× alpha

0.2700

boldest claim

The sentences

a significant trendp = 0.27not close (p > 0.1)

Those carrying both Bw4Ile80 and KIR3DS1 did not display a significant trend towards higher CD4+ T cell counts over the period of observation (+ 40 cells/uL [SE = 36.5], p = 0.27, Figure 1 C), and displayed a trend towards a reduction in viral loads (−0.22 log 10 [SE = 0.15] lower HIV-1 RNA copies/mL, p = 0.14, Figure 1 C) relative to those who did not carry both genes.

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marginally significantno p-value reported

Those with both Bw4Ile80 and KIR3DS1 demonstrated a marginally significant trend towards viral load reductions (−0.29 [SE = 0.19] log 10 copies/mL, p = 0.12) versus those who carried KIR3DS1 alone.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.