Genetic analyses of longitudinal phenotype data: a comparison of univariate methods and a multivariate approach.

BMC Genet · 2003 · PMC1866464 · PMID 14975097

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a clear trendno p-value reported

Using the third approach, the QTL h 2 for the two baseline genes were nearly flat and slightly declining with age, but that of the slope gene showed a clear trend of monotonic increase with age, which distinguished the slope gene from the baseline genes.

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