Conclusion It is essential that formal procedures be adopted in order to avoid modestly positively results from candidate regions being swamped by the huge number of nominally significant results which will be obtained when very many markers are genotyped.
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A pragmatic suggestion for dealing with results for candidate genes obtained from genome wide association studies.
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The sentences
If there are particular markers which are incorporated in the genome scan which do happen to be strongly associated with the disease then it is true that they may produce very highly significant p values.