Barely Significant
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Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach.

BMC Psychiatry · 2007 · PMC1888684 · PMID 17521439

Europe PMCDOI
1
hedged sentence
0.0610
closest p · 1.2× alpha
0.0610
boldest claim

The sentences

showed a trendp = 0.061so close (0.05 < p ≤ 0.1)
TPH1 A779C C/A genotype was inversely associated with good treatment response when compared with non-responders [OR = 0.59 (95% Cl 0.36–0.98), p = 0.030] or with the controls [OR = 0.44 (95% CI 0.23–0.86, p = 0.016], and GNB3 C825T C/T genotype showed a trend-like positive association among the male patients with a good response compared with non-responders [OR = 3.48 (95% Cl 0.92–13.25), p = 0.061], and a clearer association when compared with the controls [OR = 4.95 (95% CI 1.56–15.70), p = 0.004].

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