showed a trendp = 0.053
Visual assessment of the intensity of TRPV3 and TRPV4 immunostaining in keratinocytes in diabetic skin showed a trend for decrease of TRPV3 [median (range) control 1.5 (1.0–2.5), diabetic 1.0 (0.5–2.0), p = 0.053; Fig 11 ] but not TRPV4 (not shown).