showed a trendp = 0.001
Although our data showed a trend towards an association between the cagA -positive, vacA s1m2 genotype and PUD (χ 2 = 13.849; p = 0.001), logistic regression analysis suggested that this could be explained by a higher prevalence of the cagA and vacA s1 alleles (OR = 5.42, 95% CI 2.6–11.3, p = 0.0006) This finding agrees with those of others reports and suggests a possible role for these factors in the pathogenesis of H. pylori -related peptic ulceration [ 3 , 4 ].