Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence.

Radiat Oncol · 2007 · PMC1971057 · PMID 17623063

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borderline significantno p-value reported

A borderline significant association with breast cancer risk was found for the 1229 T>C (Val>Ala) substitution in exon 11 (P-value 0.055) between the Norwegian controls and breast cancer patients as well as a borderline significant difference in haplotype distribution (P-value 0.06).

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did not reach statistical significanceno p-value reported

Haplotype associations Risk for developing breast cancer A trend for difference in frequency distribution of the haplotypes of the ATM gene was found between cases and controls when including all identified variants, (P-value 0.06) but it did not reach statistical significance.

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