Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae.

There were no significant differences in the score for the degree of histological inflammation of the lungs 4 h after inoculation (a median score of 15 for both Apcs −/− and wild-type mice), and although there was an increase in the inflammation score 24 h after infection in the lungs from Apcs −/− mice, with a median score of 70 (IQR 60–80) compared to a median score of 30 (IQR 19–68) for wild-type mice, this did not reach statistical significance ( p = 0.48).

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