The effect of the synthetic retinoid etretinate on sputum cytology: results from a randomised trial.

and it is unlikely therefore, that inaccurrate sputum cytodiagnosis significantly affected the outcome, as there is not even a slight trend, in favour of the active treatment arm.

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For several other symptoms (dry skin, itching and hair loss) there was a trend towards a mildly toxic effect of etretinate, but the differences did not reach statistical significance.

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