Increased p53 protein content of colorectal tumours correlates with poor survival.

Br J Cancer · 1992 · PMC1977434 · PMID 1419618

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0700

boldest claim

The sentences

highly significantP<0.0001actually significant

No significant correlation was found with Dukes' stage (P= 0.15), but a highly significant correlation was obtained with DNA index > 1.30 (P<0.0001) as well as 17p loss (P< 0.002). p53 content was also significantly different when it was compared to tumour site (P<0.03), with a considerably reduced incidence in the proximal colon (42.1% positive cases) compared to an average of 74.8% in the distal seg- ments. r- U- 0 30 60 FL2 b 0 30 60 FL2 C 0 30 60 FL2 Figure 4 p53/DNA FCM results for a tumour of the rectum (DNA index 1.15).

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did not reach statistical significanceP<0.07so close (0.05 < p ≤ 0.1)

The analysis was repeated after exclusion of the 14 stage D patients (not shown); in this case the differ- ence did not reach statistical significance (P<0.07).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.