Prognostic significance of p53 overexpression in gastric and colorectal carcinoma.

Br J Cancer · 1992 · PMC1977927 · PMID 1520594

Europe PMC DOI

hedged sentences

0.2700

closest p · 5.4× alpha

0.2700

boldest claim

The sentences

did not reach statistical significanceP = 0.27not close (p > 0.1)

In gastric cancer p53 overexpression was detected most frequently in tumours from the cardia but the difference did not reach statistical significance (P = 0.27) and was irrespective of macroscopic configuration.

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highly significantno p-value reported

Thus, no variations were found in colorectal carcinoma for the 35 tumours tested but one of the 25 gastric cancers tested was positive for p53 on the frozen material and negative on the paraffin section. The relationship between p53 expression and several clin- ico-pathological criteria related to prognosis is shown in Table II for gastric and Table III for colorectal carcinoma. There is a highly significant correlation between p53 expres- sion and tumour stage in gastric and colorectal carcinoma.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.