Chlorambucil-monoglutathionyl conjugate is sequestered by human alpha class glutathione S-transferases.

Br J Cancer · 1992 · PMC1977928 · PMID 1520581

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of marginal significanceno p-value reported

The results presented here show that at physiological pH; with concentrations of salts, GSH and GSTs approxi- mating those in cells, and amounts of CHB and time periods similar to those pertaining to chemotherapy, the catalysis of CHB conjugation with GSH is of marginal significance com- pared to the non-catalytic reaction.

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