TGF-β receptor expressing cases showed a trend towards lower rates of distant metastasis, although this difference was not significant (table 2 ; 24.5% vs. 12.3%; p = 0.072 for type 1 and 25.4% vs. 16.6%, p = 0.087 for type 2).
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TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study.
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