Frequent mutations of p53 gene in oesophageal squamous cell carcinomas with and without human papillomavirus (HPV) involvement suggest the dominant role of environmental carcinogens in oesophageal carcinogenesis.

Br J Cancer · 1994 · PMC2033483 · PMID 8054284

Europe PMC DOI

hedged sentence

0.1946

closest p · 3.9× alpha

0.1946

boldest claim

The sentences

did not reach statistical significanceP = 0.1946not close (p > 0.1)

Although mutations were more common in HPV-negative tumours (50.0% vs 22.2%), the difference in p53 mutations in HPV-positive and -negative tumours did not reach statistical significance (P = 0.1946).

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