Barely Significant
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The detection of ductal carcinoma in situ at mammographic screening enables the diagnosis of small, grade 3 invasive tumours.

Br J Cancer · 1997 · PMC2063314 · PMID 9052407

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Grade 3 tumours with either no associated DCIS or DCIS only within the invasive component were significantly larger in size than tumours with surrounding DCIS (P<0.02) and were less likely to be under or equal to 10 mm in size (0% or 13% vs 30% respectively, P<0.02). There was a trend for tumours with surrounding DCIS to have less frequent nodal involvement than the other two groups, but this did not reach statistical significance (28% vs 42% and 43% respectively).

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