PPI-QTLs on Chromosomes 1, 3, 7, and 10; ASR-QTLs on Chromosomes 2, 11, and 16; and latency-QTLs on Chromosomes 4, 13, and 15 fulfilled the criteria for highly significant linkage (genome-wise p- value < 0.01) ( Table S6 ).
In the adult frontal cortex, C3 mice showed a trend of increased expression of Fabp7 .
We observed significant differences between C57BL/6 (B6) and the other strains, as well as marginally significant sex effect by analysis of variance based on the linear mixed model, in PPI magnitude ( Table S1 , see Materials and Methods for details).