Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?

After correction for multiple comparisons, we found a modestly significant association between a haplotype in the GABA-β1 receptor subunit with motor limitation scores.

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The two SNPs in the α-2C adrenergic receptor that were nominally significant in the additive model (without correction for multiple tests, Table 4 ) made small contributions to the variance in movement scores – approximately 0.6% and 0.9% (partial R 2 ).

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