None of the other variables approached significance when these two were in the model.
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Proliferative response of human prostate tumour xenografts to surgical trauma and the transurethral resection of the prostate controversy.
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None of the other variables approached significance when these two were in the model. The influence of TURP on metastatic disease has received considerable attention and remains a controversial subject. The majority of radiation studies find a highly significant correlation between TURP in stage C disease and increased subsequent metastases (Hanks et al., 1983; Forman et al., 1986; McGowan 1987; Perez et al., 1989; Amdur et al., 1990) but there are reports that such an association does not exist (Anscher and Prosnitz, 1991) or that it can be totally explained by the correlation between TURP and other fac- tors, such as grade, which actually account for the heigh- tened metastatic rates in patients undergoing TURP (Kuban et al., 1987).