MIF addition also appeared to up-regulate JNK-1/2 phosphorylation when compared with differentiation medium alone; however, this effect was not as pronounced as for ERK-1/2 and did not reach statistical significance (96 h, P < 0.06; Fig. 4 B ).
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A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia.
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