In this case a combination of 24.5 mg/kg/day vinclozolin, 0.77 mg/kg/day flutamide and 14.1 mg/kg/day procymidone induced half-maximal AGD alterations, but the effects induced by each chemical on its own did not reach statistical significance when compared with effects in untreated controls.
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Combined exposure to anti-androgens exacerbates disruption of sexual differentiation in the rat.
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