Exploring the sequence space of a DNA aptamer using microarrays.

Nucleic Acids Res · 2007 · PMC2190713 · PMID 17981839

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quite significantno p-value reported

As shown in Figure 5 , changes in the base pairs 5 through 8 (which would correspond to the initial stem region just below the loop in the consensus sequence and proposed secondary structure) have quite significant effects on the observed binding signal.

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