B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).

J Exp Med · 1999 · PMC2192978 · PMID 9892625

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closest p · 1.0× alpha

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The sentences

did not reach statistical significanceP > 0.05actually significant

The difference in survival between the CTLA-4/B7-1 −/− and the CTLA-4 −/− (mean = 17.5 d; n = 11) strains did not reach statistical significance ( P > 0.05; Fig. 1 ).

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