Although the numbers of peritoneal neutrophils and macrophages appeared lower in the BLTR −/ − mice at some time points, the differences from wild type did not reach statistical significance for either of these cell types ( Fig. 5 A).
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BLTR mediates leukotriene B(4)-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis.
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