Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.

Both granulocytes and total lymphocytes, as well as subpopulations of CD4 + and CD8 + T cells, showed a biphasic decline in telomere length that was rapid during early childhood and more gradual, although still highly significant, thereafter.

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The average telomere fluorescence values in both cell populations were slightly higher in female than in male donors; however, this difference did not reach statistical significance (results not shown).

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