Although there was a small decrease of viral capture for DC-SIGN − DCs, it did not reach statistical significance when compared with DCs transduced with an empty vector (mean ± SD: 77 ± 12% vs. 84 ± 5%, respectively; Fig. 2 C).
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DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells.
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