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Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade.

J Exp Med · 2005 · PMC2213182 · PMID 15851489

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a clear trendno p-value reported
Seven of nine cleared symptoms and laboratory abnormalities within days to weeks of therapy initiation; one patient showed a clear trend toward improvement.

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