Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking.

PLoS Med · 2007 · PMC2222948 · PMID 18162041

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

failed to reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

The rarest haplotype (4:AC, associated with high CRP plasma level [ 21 ]) was more prevalent in cases; however, the overall haplotype distribution in cases and controls failed to reach statistical significance ( p = 0.06), and using conventional logistic regression the weak association was attenuated by adjustment for carriage of LOC387715 haplotype 2 and smoking.

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