IgE alone promotes human lung mast cell survival through the autocrine production of IL-6.

BMC Immunol · 2008 · PMC2257927 · PMID 18215266

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did not reach statistical significanceno p-value reported

A study of the effects of anti-IgE therapy (omalizumab) on airway inflammation in asthma identified a downward trend in both epithelial and lamina propria mast cell numbers of approximately 20% compared to control although this did not reach statistical significance [ 28 ].

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