The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system.

PLoS One · 2008 · PMC2258435 · PMID 18335063

Europe PMC DOI

hedged sentence

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

showed a trendP = 0.052so close (0.05 < p ≤ 0.1)

Anandamide levels showed a trend towards an increase following ghrelin treatment in WT mice (control 15.9±1.8 vs. ghrelin 19.9±3.12 fmol/mg, P = 0.052, Fig. 1E ), whereas no effect was observed in CB1-KO mice (control 18.5±5.6 vs. ghrelin 20.9±8.7 fmol/mg, Fig. 1E ).

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