Barely Significant
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The impact of the human DNA topoisomerase II C-terminal domain on activity.

PLoS One · 2008 · PMC2262138 · PMID 18335031

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a clear trendno p-value reported
While the absence of the C-terminal domain for topoIIα or β had no effect on strand passage activity, the presence of the C-terminal domain from the opposite isoform had a noticeable effect with a clear trend emerging.

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