Multiple oncogenic pathway signatures show coordinate expression patterns in human prostate tumors.

For example, of the 559 genes in the Chen androgen signature (448 of which were represented in at least three prostate tumor datasets), 29 were correlated ( p <0.05) with KLK3 in at least three out of the four prostate tumor datasets; by chance, nine were expected, and so the amount of actual overlap was quite significant ( p = 1.2E-08).

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