AA patients showed a trend to lower IL-10 production than AG/GG patients, although the difference was not statistically significant probably due to the small number of patients analyzed.
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A phase I clinical study of vaccination of melanoma patients with dendritic cells loaded with allogeneic apoptotic/necrotic melanoma cells. Analysis of toxicity and immune response to the vaccine and of IL-10 -1082 promoter genotype as predictor of disease progression.
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