A dilution series illustrated a clear trend towards an increase in cell death at treatment with as little as approximately 5 to 10 pg SecTRAP, but at least 100 pg was needed to give a statistically significant increased cytotoxicity using A549 cells treated for 4 h ( Fig. 2B ).
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Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells.
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