Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction.

Part Fibre Toxicol · 2008 · PMC2276228 · PMID 18269765

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At a deposition of 19–20 μg, fine TiO 2 showed a trend towards an impaired dilation, while ultrafine TiO 2 produced arteriolar constrictions that were significantly different from the responses in both the sham-control and fine TiO 2 groups (Middle Panel).

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