Barely Significant
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HIPEC: the complexities of clinical trials.

Ann Surg Oncol · 2008 · PMC2277452 · PMID 18324445

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quite significantno p-value reported
Nevertheless, the consequence of an anastamotic leak is quite significant, and it would be very difficult to continue to dose escalate if there was any chance that the leak was related to the dose of adriamycin.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.