Although a similar trend was observed among optimally debulked patients, the prognostic impact did not reach statistical significance ( Spentzos et al , 2004 , 2005 ).
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Independent prognostic significance of cell cycle regulator proteins p16(INK4a) and pRb in advanced-stage ovarian carcinoma including optimally debulked patients: a translational research subprotocol of a randomised study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group.
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