Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.

Br J Cancer · 2007 · PMC2360430 · PMID 17912246

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did not reach statistical significanceno p-value reported

By day 4, the plasma dUrd levels remained elevated relative to baseline, although this did not reach statistical significance (103 nmol l −1 , 154%, NS).

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