Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC study.

Br J Cancer · 2006 · PMC2361124 · PMID 16404426

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nominally significantno p-value reported

In summary, the main findings of our study were thus a weak but nominally significant association of a block of polymorphisms located at the 5′ end of the IGF1 gene with breast cancer risk, particularly among women younger than 55 years, and an association of polymorphisms located in the 5′ region of IGFBP3 with circulating levels of IGFBP-3.

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