Expression and localisation of Akt-1, Akt-2 and Akt-3 correlate with clinical outcome of prostate cancer patients.

Br J Cancer · 2006 · PMC2361354 · PMID 16721361

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.1000

boldest claim

The sentences

borderline significantP =0.07so close (0.05 < p ≤ 0.1)

In addition, Akt-2 was also significantly associated with earlier PSA relapse ( P =0.02, log rank test, Figure 3B and Table 3 ) while Akt-3 and phospho-Akt were borderline significant ( P =0.07, P =0.06, respectively, log rank, Table 3 , Figure 3C and D ).

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showed a trendP =0.08so close (0.05 < p ≤ 0.1)

In contrast, nuclear Akt-2 in cancerous tissues was not significantly associated with any parameter tested, but only showed a trend to correlate inversely with perineural infiltration and lymph node invasion ( r =−0.22, P =0.08, Table 2 ).

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a weak trendP =0.10so close (0.05 < p ≤ 0.1)

We also noticed a weak trend of cytoplasmic Akt-1 expression to correlate inversely with PSA recurrence-free interval ( r =−0.28, P =0.10, Spearman's test).

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