Meta-analysis of randomised adjuvant therapy trials for pancreatic cancer.

Br J Cancer · 2005 · PMC2361989 · PMID 15812554

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a nonsignificant trendno p-value reported

The EORTC trial showed a nonsignificant trend in favour of chemoradiation with a 30% reduction in the risk of death and the ESPAC1-2 × 2 and the ESPAC1-plus trials showed nonsignificant trends in favour of no chemoradiation with 28 and 8% increase in the risk of death, respectively.

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a significant trendno p-value reported

The Norwegian trial showed a nonsignificant trend in favour of treatment with a 20% reduction in the risk of death, the Japanese trial showed a nonsignificant trend in favour of no treatment with an 18% increase in the risk of death and the ESPAC1-2 × 2 and ESPAC1-plus trials showed a significant trend in favour of chemotherapy with 29 and 46% reduction in the risk of death with chemotherapy, respectively.

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