The difference did not reach statistical significance at univariate log-rank test ( P =0.48) or at Cox's multivariate analysis (HR=0.84; 95% CI: 0.54–1.32).
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A randomised factorial trial of sequential doxorubicin and CMF vs CMF and chemotherapy alone vs chemotherapy followed by goserelin plus tamoxifen as adjuvant treatment of node-positive breast cancer.
2
0.4800
0.4800
The sentences
At a median follow-up of 6.2 years, there was a trend in favour of improved DFS for the addition of goserelin to CAF, although this just failed to reach statistical significance.