Comparative pharmacology of oral fluoropyrimidines: a focus on pharmacokinetics, pharmacodynamics and pharmacomodulation.

Br J Cancer · 2004 · PMC2364788 · PMID 15280932

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did not reach statistical significanceno p-value reported

These differences, however, did not reach statistical significance and the authors concluded that in patients with mild-to-moderately impaired hepatic function there is no need to adjust the dose.

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