Barely Significant
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Increased antibodies against unfolded viral antigens in the elderly after influenza vaccination.

Influenza Other Respir Viruses · 2007 · PMC2367137 · PMID 18458742

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a significant trendno p-value reported
There was a significant trend toward an increased proportion of antibodies to denatured antigens with increasing dosage of vaccine ( Figure 3 ), especially in avidity, even though there were only 10 subjects given each dose.

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