Barely Significant
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HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model.

PLoS One · 2008 · PMC2373517 · PMID 18463734

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a clear trendno p-value reported
Remarkably, after 106 treatment gene expression profiles showed a clear trend toward normalization.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.