Hepatitis C virus diversity and evolution in the full open-reading frame during antiviral therapy.

PLoS One · 2008 · PMC2373758 · PMID 18463735

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did not reach statistical significanceno p-value reported

Core (p = 0.046), E1 (p = 0.006), NS4B (p = 0.023), and NS5A (p = 0.041) had statistically significant increases in protein distance during therapy, and many of the other proteins, including the polyprotein, had increases that did not reach statistical significance.

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