Barely Significant
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Hybrid optimization method with general switching strategy for parameter estimation.

BMC Syst Biol · 2008 · PMC2373877 · PMID 18366722

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quite significantno p-value reported
Even for this rather simple example the chance of getting trapped in a local solution or to fail is quite significant and increases with increasing noise to signal ratio.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.