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Effector CD8+CD45RO-CD27-T cells have signalling defects in patients with squamous cell carcinoma of the head and neck.

Br J Cancer · 2003 · PMC2377049 · PMID 12610507

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Indeed, the overall proportion of naïve CD8 + CD45RA + T cells (including effector cells) was somewhat lower and that of memory CD8 + CD45RO + cells higher in patients than in controls ( Figure 1 ) although these differences did not reach statistical significance.

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