The overall four-factor repeated measures ANOVA revealed a significant main effect of location (F [ 1 , 15 ] = 15.4, p < 0.01), main effect of time (F [3, 45] = 3.1, p < 0.05), and main effect of side (F [ 1 , 15 ] = 5.7, p < 0.05), and a location × side interaction that approached significance (F[ 1 , 15 ]= 4.27, p = 0.0565).
With regard to the primary variable of interest in the current study, however, there was no significant main effect of duration, but there was an interaction of duration and time (F [6,90] = 2.23, p < 0.05), with the longest duration of stimulation (30 min) producing less change from pre-stimulation baseline than the shortest duration (5 min); the remaining interactions with the duration factor did not achieve significance (all F's < 1.41, P's > 0.20). 2) Warm Sensation Threshold The overall four-factor repeated measures ANOVA revealed a significant main effect of location (F [1, 15] = 82.9, p < 0.0001), significant main effect of time (F [3, 45] = 35.7, p < 0.0001), and significant interactions of location and time (F [3, 45] = 8.0, p < 0.001) as well as location × side × time (F [3,45] = 4.89, p < 0.005).